What is Mesotherapy with Stem Cells and PRP?
Mesotherapy with stem cells and PRP (Platelet-Rich Plasma) is a modern biological treatment for skin regeneration and renewal, which harnesses the regenerative properties of the patient’s own cells. The method is based on processing the patient’s own blood to isolate plasma rich in platelets and growth factors. When this material is injected into the skin, it stimulates collagen and elastin production, enhances microcirculation, and activates tissue repair mechanisms.
In recent years, PRP mesotherapy has been combined with techniques for isolating stem cells or cellular factors from fat tissue or blood, adding even greater regenerative power to the treatment. Its action is entirely natural, without chemicals or synthetic additives, and it is suitable for the face as well as the scalp, neck, décolleté, and hands. Essentially, it is one of the most advanced cellular regeneration treatments, ideal for faces showing early or moderate signs of aging.

How is the procedure performed?
The PRP mesotherapy procedure begins with a small blood draw from the patient, similar to a routine blood test. The blood is placed in special tubes and centrifuged to separate the plasma that contains a high concentration of platelets, cytokines, and growth factors. In some protocols, an activating factor (e.g., calcium) may be added, or the preparation may be enhanced with mesenchymal cells from adipose tissue or bone marrow.
The produced PRP is injected intradermally or subcutaneously into the treatment area through microinjections using mesotherapy technique. The application is painless or minimally uncomfortable and lasts about 30–45 minutes. In most cases, a topical anesthetic cream is applied before the session to ensure patient comfort.
After treatment, the skin may show mild redness or slight swelling, which subsides within 24–48 hours. The patient can immediately return to daily activities but should avoid sun exposure and makeup for one day. The treatment is usually repeated every 3–4 weeks for an initial 3 sessions, then 1–2 times per year for maintenance.
What are the benefits of PRP mesotherapy?
Mesotherapy with PRP and stem cells offers several advantages that make it unique in its category. First and foremost, it is completely safe since it uses autologous material, meaning material derived from the patient’s own body. This eliminates the risk of allergic reaction, rejection, or infection, making it suitable even for patients with sensitivities or chronic conditions.
The treatment enhances the skin’s natural regenerative mechanisms, improving elasticity, tightening, reducing fine lines, and evening out skin tone. Additionally, it helps reduce hair loss and rejuvenates the scalp, especially in early androgenetic alopecia cases. Its action is gentle, gradual, and long-lasting, without causing unnatural tension or distortion of facial features.
Another important advantage is the ability to combine it with other treatments such as fractional laser, microneedling, hyaluronic acid, or Botox, for a comprehensive anti-aging approach. Unlike more invasive methods, PRP mesotherapy offers freshness, radiance, and texture improvement without downtime or significant side effects.

Χωρίς τομές
Certified method
Impressive & instantly visible results
Multiple application areas
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Frequently Asked Questions
Absolutely. Since the patient’s own blood is used and the procedure follows medical protocols, the risk of side effects is extremely low. The only discomfort may be a mild stinging sensation during injection.
Improvement is gradual. Initial signs of renewal are visible after 2–3 weeks, with maximum results developing within 2 months. Skin texture, elasticity, and radiance progressively improve.
The effects last approximately 6–9 months, depending on skin type and lifestyle. For better maintenance, repeat sessions every six months are recommended.
Yes, it is highly effective when combined with laser, microneedling, threads, and injectables, as it enhances healing and multiplies results.
The treatment uses fine needles and is well tolerated by most patients. The use of topical anesthesia further minimizes discomfort.
Yes, the treatment is suitable for all skin phototypes and types, regardless of age or gender.
Mesotherapy with PRP and stem cells is one of the most innovative biological regeneration treatments, providing natural and long-lasting results. Without chemicals or deformities, it activates the body’s own biology and offers a holistic approach to anti-aging and skin renewal.
Plastic Surgeon Eleftherios Dimitradiou utilizes advanced PRP and cellular regeneration protocols, aiming to restore skin health and radiance, based on evidence-based medical techniques and personalized care.
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